Metastatic lung cancer in pregnancy - a diagnostic and management challenge: A case report

Authors

  • Dr. Mwangi C.M Department of Obstetrics and Gynecology, University of Nairobi, Nairobi, Kenya.
  • Dr. Omwodo K.A Department of Reproductive Health, Moi University, Eldoret, Kenya.
  • Dr. Osoti A.O Senior Lecturer, Consultant Obstetrician-Gynecologist, Clinical Epidemiologist, University of Nairobi, Nairobi, Kenya, Associate Professor of Global Health – Public Health, University of Washington, Washington, United States.

DOI:

https://doi.org/10.59692/jogeca.v33i2.440

Keywords:

Lung cancer, Small cell carcinoma, pulmonary tuberculosis

Abstract

Background: Lung cancer during pregnancy remains an uncommon occurrence. As of 2016, there were less than 70 histologically confirmed lung cancer in pregnancy cases reported in the literature. 

Case presentation: A 29-year-old woman presented with a chronic cough in the second trimester of pregnancy at the Kenyatta National Hospital (KNH) as a referral. Treatment for Pulmonary Tuberculosis (PTB) was initiated in a peripheral facility based on suggestive signs on the chest radiograph. Symptoms persisted while on anti-TB medication. On further evaluation, she was diagnosed with advanced squamous cell lung cancer. The patient went into spontaneous labor and vaginally delivered a fresh stillbirth. She received palliative care, and succumbed from disease progression.  

Conclusion: Lung cancer during pregnancy exhibits similar clinical presentation to prevalent conditions, especially in low-resource and TB prevalent settings, and pose challenges in early diagnosis, and consequently, poor outcome. Chronic cough should raise suspicion for malignancy and prompt investigation. 

Author Biographies

Dr. Mwangi C.M, Department of Obstetrics and Gynecology, University of Nairobi, Nairobi, Kenya.

  Department of Obstetrics and Gynecology, University of Nairobi, Nairobi, Kenya.

Dr. Omwodo K.A, Department of Reproductive Health, Moi University, Eldoret, Kenya.

 Department of Reproductive Health, Moi University, Eldoret, Kenya.

Dr. Osoti A.O, Senior Lecturer, Consultant Obstetrician-Gynecologist, Clinical Epidemiologist, University of Nairobi, Nairobi, Kenya, Associate Professor of Global Health – Public Health, University of Washington, Washington, United States.

Senior Lecturer, Consultant Obstetrician-Gynecologist, Clinical Epidemiologist, University of Nairobi,  Nairobi, Kenya.

Associate Professor of  Global Health – Public Health, University of Washington, Washington, United States.

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Published

2021-03-31

How to Cite

Mwangi, C., Omwodo, K., & Osoti, A. (2021). Metastatic lung cancer in pregnancy - a diagnostic and management challenge: A case report. Journal of Obstetrics and Gynaecology of Eastern and Central Africa, 33(2), 51–54. https://doi.org/10.59692/jogeca.v33i2.440